![]() ![]() Hemos comparado las características de tres sistemas de diagnóstico rápido de HbA1c respecto al método de referencia constituido por la cromatografía líquida de alta resolución (HPLC). Only the Afinion AS100 point-of-care system met all NGSP performance criteria.Įl uso de sistemas de determinación rápida de HbA1c proporciona resultados inmediatos y reduce inconvenientes para los pacientes. The coefficients of variation for Afinion AS100, DCA Vantage and In2it systems were 1.80, 3.74 and 7.14%, respectively. The 95% confidence interval of the error between point-of-care systems and the reference method was −0.41% and +0.34% ( p = 0.22) for Afinion AS100, −0.62% and +0.05% ( p = 0.57) for DCA Vantage, and −1.15% and +1.26% ( p < 0.001) for the In2it. The calculated correlation coefficients ( r) were 0.98, 0.98 and 0.83 for Afinion AS100, DCA Vantage and In2it systems, respectively. We used the acceptability criteria endorsed by the National Glycohemoglobin Standardization Program. According the Clinical Laboratory Standards Institute EP-09 protocol we determined linearity (linear regression and correlation coefficient between point-of-care and reference methods), bias (Bland–Altman analysis) and coefficient of variation (%). Aliquots of theses samples were tested by Afinion AS100, DCA Vantage and In2it point-of-care systems. We preselected a pool of 40 EDTA-preserved whole blood samples from our laboratory with HbA1c results obtained by HPLC (mean 6.6% and range: 4.6–9.9% ). We compared the analytical performances of 3 point-of-care HbA 1c analyzers to high pressure liquid chromatography (HPLC). Use of hemoglobin A1c point-of-care devices in physician offices provides immediate results and reduces inconveniences for the patients. ![]()
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